Bullosis Diabeticorum

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E13.628 – Other specified diabetes mellitus with other skin complications

48951005 – Bullosis diabeticorum


Bullosis diabeticorum (BD), also known as bullous eruption of diabetes mellitus or diabetic bullae, occurs in about 0.5% of diabetics and has an unknown pathogenesis. The bullae are painless and develop rapidly and spontaneously. Typically, there are no other symptoms except for pruritus. BD is typically seen in long-term diabetics, although there have been reports of BD as the presenting sign of diabetes. Recurrence is common, and new bullae can continue to form over a period of years. The average age of onset is 55 years, and there is a 2:1 male-to-female ratio.

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