Drug Eruption, Exanthematous

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Image of Drug Eruption, Exanthematous

VisualDx images show variation in age, skin color, and disease stage. VisualDx has 87 images of Drug Eruption, Exanthematous.

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ICD Codes

L27.0 – Generalized skin eruption due to drugs and medicaments taken internally

693.0 – Dermatitis due to drugs and medicines taken internally


Exanthematous or morbilliform eruptions are the most common of all medication-induced eruptions. They consist of red macules and papules that often arise on the trunk and spread symmetrically to involve the proximal extremities. In severe eruptions, lesions coalesce and may lead to erythroderma. Palms, soles and mucous membranes also may be involved. Pruritus is common and fever may occur in more severe reactions. Onset is usually within 7-14 days of initiating a medication.

Almost any oral agent can cause an exanthematous reaction, but they are most commonly seen with the use of antibiotics (penicillins and sulfas), allopurinol, phenytoin, barbiturates, chlorpromazine, carbamazepine, gold, d-penicillamine, captopril, naproxen, and piroxicam, among others.

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