Drug Eruption, Fixed
Image and content excerpted from the VisualDx clinical decision support system.
VisualDx images show variation in age, skin color, and disease stage. VisualDx has 152 images of Drug Eruption, Fixed.
Full text and additional images for Drug Eruption, Fixed are available in the following VisualDx packages:
L27.1 – Localized skin eruption due to drugs and medicaments taken internally
693.0 – Dermatitis due to drugs and medicines taken internally
SynopsisFixed drug eruption (FDE) is an adverse drug reaction manifested by skin lesions occurring at the same body site each time the individual is re-exposed to the specific drug. It is most frequently solitary but may sometimes be multiple. Lesions are usually asymptomatic but may cause burning or pruritus. Sometimes these lesions will form blisters. Post-inflammatory hyperpigmentation is common.
While over 100 drugs have been implicated in causing FDE, commonly associated drugs include trimethoprim-sulfamethoxazole (and other sulfonamides), naproxen, ibuprofen, tetracyclines, other antibiotics (ampicillin, metronidazole), barbiturates, oral contraceptives, quinine, and phenolphthalein.