Image and content excerpted from the VisualDx clinical decision support system.
VisualDx images show variation in age, skin color, and disease stage. VisualDx has 69 images of Hand-Foot-and-Mouth Disease.
Full text and additional images for Hand-Foot-and-Mouth Disease are available in VisualDx.
Sign up for a Free 30-Day Trial of VisualDx.
B08.8 – Other specified viral infections characterized by skin and mucous membrane lesions
266108008 – Hand foot and mouth disease
SynopsisHand-foot-and-mouth disease (HFMD) is an acute, self-limited, viral illness caused most often by Coxsackievirus A16, though it can be caused by other coxsackieviruses and enteroviruses. HFMD affects children most often, but adults can also develop the disease. The incubation period is short, ranging from 3 to 6 days. The illness begins with a mild fever, sore throat and mouth, cough, headache, malaise, diarrhea, and occasionally arthralgias. One or two days after the onset of fever, small oral vesicles develop. Later, vesicles appear on the hands, feet, and occasionally the buttocks.
The disease is highly contagious, and it spreads via aerosolized droplets, nasal or oral secretions, or fecal material. Outbreaks usually occur from June to October. Though HFMD is typically self-limited, it can be complicated by encephalitis and other life-threatening complications. These complications include interstitial pneumonia, myocarditis, meningoencephalitis, and spontaneous abortion. Complications are more common when the disease is caused by an enterovirus, particularly Enterovirus EV-A71.