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L85.8 – Other specified epidermal thickening
5132005 – Keratosis pilaris
SynopsisKeratosis pilaris is an exceedingly common benign skin disorder of the follicular orifice. It is commonly referred to as "gooseflesh." It is characterized by small follicular papules on the extensor lateral extremities due to the retention of keratin at the follicular opening. It is frequently seen in adolescents and young adults, rarely in the elderly. Women are affected slightly more often than men. Dry weather often worsens the condition. Frequently, there is a family history of the condition. Autosomal dominant inheritance with variable penetrance has been described. Keratosis pilaris tends to be refractory to most treatments with complete cure highly unlikely; however, the condition tends to improve with age.
Keratosis pilaris most often occurs as described above but does have 3 main clinical variants: keratosis pilaris atrophicans faciei, atrophoderma vermiculatum, and keratosis follicularis spinulosa decalvans. All of these entities have hyperkeratotic follicular papules with varying degrees of atrophy. Keratosis pilaris atrophicans faciei is characterized by erythematous hyperkeratotic papules distributed on the lateral third of the eyebrows in young children. Atrophoderma vermiculatum (also termed honeycomb atrophy) is characterized by atrophic pits in a reticulate or worm-eaten array localized to the face of older children. Keratosis follicularis spinulosa decalvans is a disorder characterized by widespread keratosis pilaris, scarring alopecia, and eye abnormalities.
Keratosis pilaris is seen with increased incidence in several syndromes and disease states. These include atopic dermatitis, ichthyosis vulgaris, erythromelanosis follicularis faciei et colli (erythema, brown pigmentation, and keratosis pilaris), Lassueur-Graham-Little-Piccardi syndrome (cicatricial alopecia of the scalp, loss of pubic and axillary hairs, and keratosis pilaris), cardiofaciocutaneous syndrome, Noonan syndrome, diabetes, Down syndrome, woolly hair, and obesity.
For more information, see OMIM.