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Temporal Variation

Additionally, the appearance of skin lesions of a disease can evolve over time.

Despite the causes of the visual complexity, and no matter when a patient is evaluated on the timeline of the disease process, accurate identification of morphology and classifications of skin lesions are the keys to diagnosing a patient's skin condition.

This series of pictures demonstrates the evolution of lesions in a patient with zoster (shingles).

Zoster (Shingles)

Day 1: Grouped umbilicated vesicles form within a dermatomal skin distribution

Day 1: Grouped umbilicated vesicles form within a dermatomal skin distribution

 

Day 5: Vesicles have crusted, and small erosions occur where crusts have "fallen off"

Day 5: Vesicles have crusted, and small erosions occur where crusts have "fallen off"

 

Day 6: More crusts forming and redness decreasing

Day 6: More crusts forming and redness decreasing

 

Day 7: Crusts have resolved

Day 7: Crusts have resolved

 

Day 21: Hypopigmented macules, small scars, and no redness (inflammation)

Day 21: Hypopigmented macules, small scars, and no redness (inflammation)