Acinar cell carcinoma
Findings include abdominal pain, a pancreatic mass, nausea, fatigue, weakness, elevated lipase, and weight loss. Some patients present with Schmid's triad (subcutaneous fat necrosis, polyarthritis, and eosinophilia) caused by elevated lipase secreted by the tumor.
Acinar cell carcinomas can easily be differentiated from adenocarcinoma and pancreatic neuroendocrine tumors based on immunohistochemical stains. Overall prognosis depends on tumor size, lymph node involvement, and presence of metastasis at diagnosis.
Treatment includes surgical resection with potential chemotherapy or radiation.
Related topic: Pancreatic carcinoma
C80.1 – Malignant (primary) neoplasm, unspecified
45410002 – Acinar cell carcinoma
- Pancreatic endocrine tumor
- Solid pseudopapillary tumor
- Ductal adenocarcinoma
- Medullary carcinoma
- Acinar cell cystadenoma
- Serous microcystic adenoma
- Serous oligocystic adenoma
- Pancreatoblastoma (see pancreatic carcinoma)