Acute interstitial nephritis
Patients older than 65 appear to be more susceptible to developing acute interstitial nephritis (AIN) with medication exposures, most commonly to penicillins and cimetidine. Patients may or may not be symptomatic. Symptoms are related to the cause of AIN and to the degree of acute kidney injury. When drug induced, allergic-type symptoms of fever, rash, and eosinophilia may develop. Roughly half of patients with AIN develop oliguria.
May resolve spontaneously with withdrawal of the precipitating agent. The degree of reversal of acute kidney injury depends on the length of exposure and the extent of tubular damage.
N10 – Acute tubulo-interstitial nephritis
28637003 – Acute interstitial nephritis