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Emergency: requires immediate attention
Acute salicylate poisoning
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Emergency: requires immediate attention

Acute salicylate poisoning

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Other Resources UpToDate PubMed

Synopsis

Toxic ingestion of salicylate. Acetylsalicylic acid (aspirin) is the most common salicylate, but there are other associated medications including wart removers, methyl salicylate (oil of wintergreen), and bismuth subsalicylate (Pepto-Bismol). Toxicity may occur acutely due to a large ingestion or may be chronic from repeated overmedication for several days.

Acute salicylate toxicity:
  • Common manifestations include hyperpnea, tachypnea, tinnitus, nausea, and vomiting.
  • In severe cases, patients can have hyperthermia, encephalopathy, and pulmonary edema.
Aspirin is rapidly absorbed in the stomach, and toxic ingestions usually present within a few hours after acute overdose. Fatal aspirin intoxication can occur after ingestion of 10-30 grams in adults and 3 grams in children. Patients will exhibit signs of intoxication when serum levels are 40-50 mg/dL.

Codes

ICD10CM:
T39.091A –  Poisoning by salicylates, accidental (unintentional), initial encounter

SNOMEDCT:
7248001 – Poisoning by salicylate

Best Tests

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 09/16/2015
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Emergency: requires immediate attention
Acute salicylate poisoning
Print 1 Images
Acute salicylate poisoning : Dizziness, Seizures, Fever, Nausea/vomiting, Hypoglycemia, Mental status alteration, Metabolic acidosis, Respiratory alkalosis, Tinnitus, HR increased, RR increased
Copyright © 2018 VisualDx®. All rights reserved.