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Allergic bronchopulmonary aspergillosis
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Allergic bronchopulmonary aspergillosis

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Contributors: Neil Mendoza MD, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to the fungus Aspergillus fumigatus, a mold that is ubiquitous in the environment.

ABPA occurs in patients with asthma (1%-2% of patients with asthma) or cystic fibrosis (2%-15% of patients with cystic fibrosis). Men and women are affected equally. Most patients are young adults.

Patients present primarily with worsening of asthma symptoms. Some patients may have other symptoms including productive cough, fever, or hemoptysis. Recurrent exacerbations are common.

Central bronchiectasis can be seen on CT scan of the chest, particularly affecting airways in the central half to two-thirds of the chest.

Treatment includes systemic corticosteroids and sometimes antifungal medication.

For more information, see OMIM.

Codes

ICD10CM:
B44.81 – Allergic bronchopulmonary aspergillosis

SNOMEDCT:
37981002 – Allergic bronchopulmonary aspergillosis

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Therapy

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References

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Last Reviewed: 02/08/2017
Last Updated: 03/30/2017
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Allergic bronchopulmonary aspergillosis
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Allergic bronchopulmonary aspergillosis : Fever, IgE elevated, IgG elevated, Malaise, Productive cough, Weight loss, Dyspnea, Hemoptysis, Wheezing, EOS increased
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