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Alopecia mucinosa - Hair and Scalp
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Alopecia mucinosa - Hair and Scalp

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Contributors: Mary Gail Mercurio MD, Belinda Tan MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Follicular mucinosis, often referred to as alopecia mucinosa, is a rare condition characterized by follicular papules and indurated plaques leading to nonscarring alopecia. Although lesions can occur anywhere on the body, the face, neck, and scalp are the most common sites. The distinct histologic changes are an accumulation of mucinous material of the pilosebaceous unit, which incites an inflammatory response. The 3 clinical variants of the disease consist of the following: primary acute disorder of young persons, usually involving the face and scalp; primary chronic disorder of older persons, which can be generalized in distribution; and a secondary disorder associated with benign inflammatory conditions or malignant disease (lymphoma), also usually seen in older persons. 

Pediatric Patient Considerations:
Pediatric cases are generally of the primary acute variant. Lesions generally spontaneously resolve in a few months to a few years.

Codes

ICD10CM:
L65.2 – Alopecia mucinosa

SNOMEDCT:
27382006 – Alopecia mucinosa

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Pediatric Considerations:
Childhood follicular mucinosis may rarely be associated with Hodgkin's disease or cutaneous T-cell lymphoma.

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 09/26/2013
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Alopecia mucinosa - Hair and Scalp
See also in: Overview
Print 10 Images
View all Images (10)
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Alopecia mucinosa : Round configuration, Scattered few, Smooth plaque, Sparse eyebrows, Alopecia
Clinical image of Alopecia mucinosa
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