Natural transmission has been reported in the southern United States, in particular Texas, although the disease is much more prevalent in Mexico, Central America, and South America. Current disease control methods are significantly limiting the natural transmission in developing countries. Most primary cases in endemic areas occur in children aged younger than 10. Migration from endemic areas and rising rates of local transmission have led to an estimated 300 000 persons in the United States with chronic Chagas disease.
The disease consists of an acute illness that can be followed by chronic late sequelae in long-standing infections after years or decades. Late sequelae are a continued source of great morbidity. Risk factors include poor economic status and habitation or travel in rural areas.
B57.1 – Acute Chagas' disease without heart involvement
77506005 – American trypanosomiasis
- Arthropod bite
- Early leishmaniasis
- Chalazia or styes
- Periorbital cellulitis
- Viral conjunctivitis