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Angioma serpiginosum in Adult
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Angioma serpiginosum in Adult

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Contributors: Aman Samrao MD, Noah Craft MD, PhD
Other Resources UpToDate PubMed


Angioma serpiginosum is a benign vascular malformation that usually presents within the first two decades of life. It is more common in young females. It begins as small areas of red or violet-colored macules and papules that start to coalesce over a period of several years to achieve a "serpiginous" appearance overall.

For more information on the autosomal dominant type, see OMIM.

For more information on the X-linked type, see OMIM.


L81.7 – Pigmented purpuric dermatosis

49465005 – Angioma serpiginosum

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Petechiae – nonblanching

Pigmented purpuric dermatoses (see capillaritis) – All are nonblanching, and all show red blood cell (RBC) extravasation, perivascular lymphocytic infiltrate, and hemosiderin on biopsy.
  • Purpura annularis telangiectodes of Majocchi – Presents as annular plaques with cayenne pepper petechiae.
  • Schamberg disease – Cayenne pepper petechiae, usually on the legs of older men.
  • Pigmented purpuric lichenoid dermatitis of Gougerot and Blum – Cayenne pepper petechiae and papules in middle-aged men.

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Last Updated: 09/07/2017
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Angioma serpiginosum in Adult
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Angioma serpiginosum : Serpiginous configuration, Telangiectasia, Blanching macule
Clinical image of Angioma serpiginosum
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