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Appendiceal mucinous neoplasm
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Appendiceal mucinous neoplasm

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Appendiceal mucinous neoplasm is a rare, benign, low-grade lesion or mucocele of the appendix. It is asymptomatic in about one-fourth of cases and discovered incidentally or on imaging. Signs and symptoms include constipation, abdominal pain, abdominal tenderness, nausea, vomiting, and diarrhea. Abdominal imaging may reveal a soft-tissue mass in the right lower quadrant, with calcification of the mural. Luminal obstruction can cause acute appendicitis. Other signs include intussusception, appendicular abscess, abdominal obstruction, or palpable abdominal mass.

If complicated by pseudomyxoma peritonei with peritoneal mucinous implants and ascites, or if the neoplasm ruptures, the prognosis is less favorable. If it shares the features of mucinous cystadenocarcinoma, then the underlying tumor is believed to be malignant and shows indication of spreading beyond the appendix.

A variety of surgical techniques have been recommended depending on the malignant determination of the mucinous neoplasm. Noncarcinoid appendiceal neoplasms may be removed by right hemicolectomy. Some believe appendectomy is sufficient. Laparoscopic resection has been shown to have favorable 2-year follow-up. It is believed that any mucinous material not completely removed may cause recurrence of the neoplasm. Some recommend surgical debulking and intraperitoneal chemotherapy.


D12.1 – Benign neoplasm of appendix

450896006 – Low grade appendiceal mucinous neoplasm


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Last Updated: 02/09/2017
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Appendiceal mucinous neoplasm
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Appendiceal mucinous neoplasm : Diarrhea, Nausea, Vomiting, Constipation, RLQ pain, Palpable abdominal mass
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