Cutaneous squamous cell carcinoma in situ (SCCis), also known as Bowen disease, is defined histopathologically by malignant keratinocytes that involve the full thickness of the epidermis. This common malignancy is primarily seen in older adults and most frequently occurs on sun-exposed skin. The development of SCCis has also been associated with immunosuppression, chronic lymphocytic leukemia, radiation exposure, arsenic ingestion, and human papillomavirus (HPV). There is no sex predilection. It is frequently seen accompanying other stigmata of chronic sun damage, such as actinic keratoses, solar lentigines, and other keratinocytic carcinomas. If left untreated, SCCis can evolve into invasive SCC.
Related topic: cutaneous squamous cell carcinoma
Squamous cell carcinoma in situ - Hair and Scalp
See also in: OverviewAlerts and Notices
Important News & Links
Synopsis
Codes
ICD10CM:
D04.9 – Carcinoma in situ of skin, unspecified
SNOMEDCT:
189565007 – Squamous cell carcinoma in situ
D04.9 – Carcinoma in situ of skin, unspecified
SNOMEDCT:
189565007 – Squamous cell carcinoma in situ
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
To perform a comparison, select diagnoses from the classic differential
Subscription Required
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
References
Subscription Required
Last Reviewed:12/12/2018
Last Updated:03/17/2024
Last Updated:03/17/2024
Patient Information for Squamous cell carcinoma in situ - Hair and Scalp
Premium Feature
VisualDx Patient Handouts
Available in the Elite package
- Improve treatment compliance
- Reduce after-hours questions
- Increase patient engagement and satisfaction
- Written in clear, easy-to-understand language. No confusing jargon.
- Available in English and Spanish
- Print out or email directly to your patient
Upgrade Today
Squamous cell carcinoma in situ - Hair and Scalp
See also in: Overview