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Bronchocentric granulomatosis
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Bronchocentric granulomatosis

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Contributors: Casey Silver MD, Mary Anne Morgan MD, Michael W. Winter MD
Other Resources UpToDate PubMed

Synopsis

Bronchocentric granulomatosis is a rare disease characterized by necrotizing granulomatous inflammation beginning in and centering around the bronchiolar walls. The inciting inflammatory precipitant is often unclear. It is associated with numerous diseases of infectious and autoimmune etiologies. These include rheumatoid arthritis; viral, fungal, and mycobacterial infections; diabetes insipidus; ankylosing spondylitis; and systemic granulomatous diseases. Bronchogenic carcinoma has also been described in association with bronchocentric granulomatosis.

Symptoms include fever, cough, wheezing, dyspnea, and blood eosinophilia. Approximately half of patients are asthmatic, and the disease can be associated with Aspergillus fumigatus hypersensitivity or infection.

Related topics: Aspergillosis, Allergic bronchopulmonary aspergillosis

Codes

ICD10CM:
J98.09 – Other diseases of bronchus, not elsewhere classified

SNOMEDCT:
111901001 – Bronchocentric granulomatosis

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Therapy

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References

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Last Reviewed: 06/13/2019
Last Updated: 06/17/2019
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Bronchocentric granulomatosis
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Bronchocentric granulomatosis : Cough, Fatigue, Eosinophilia, IgE elevated, Malaise, Pleuritic chest pain, Dyspnea
Copyright © 2019 VisualDx®. All rights reserved.