Cardiac sarcoma is a rare mesenchymal neoplasm or tumor of the heart that is malignant in nature. The most common type is angiosarcoma; other manifestations include rhabdomyosarcomas, leiomyosarcomas, fibrosarcomas, and other variations. Rarely, paragangliomas may occur in the heart. Common signs and symptoms include chest pain, heart murmur, palpitations, dyspnea, night sweats, neck vein distention, weight loss, and swelling of the feet, legs, ankles, or abdomen. Diagnostic determination may be aided by echocardiography, CT, and/or MRI imaging. The malignancy infiltrates cardiac structures rapidly and upon diagnosis may have already begun metastases. Prognosis is generally poor, even with complete resection or cardiac transplant.