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Cytomegalovirus infection - Oral Mucosal Lesion
See also in: Overview,Anogenital
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Cytomegalovirus infection - Oral Mucosal Lesion

See also in: Overview,Anogenital
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Contributors: Carl Allen DDS, MSD, Sook-Bin Woo MS, DMD, MMSc
Other Resources UpToDate PubMed

Synopsis

Cytomegalovirus (CMV) infection is caused by Herpesvirus 5. A majority of adults in the United States show seropositivity by the age of 60. Patients with active infection tend to be young to middle-aged adults. CMV seropositivity prevalence tends to be higher in women of lower socioeconomic status.

Uncommon in the oral cavity, CMV presents primarily as persistent and progressive ulceration typically occurring in human immunodeficiency virus (HIV) and immunosuppressed patients. In rare cases, CMV manifests in the parotid gland. Patients often have concomitant infection of the gastrointestinal tract (bloody diarrhea) and/or the eyes (chorioretinitis). Other symptoms include lymphadenopathy, hepatosplenomegaly, esophagitis, pneumonia, and meningoencephalitis. Transmission is by body secretions, including saliva, blood, urine, breast milk, semen, and cervical fluid.

With the advent of highly active antiretroviral therapy (HAART), this oral infection has been on the decline in the United States.

Related topic: Cytomegalovirus infection of newborn, Cytomegalovirus retinitis

Codes

ICD10CM:
B25.9 – Cytomegaloviral disease, unspecified

SNOMEDCT:
28944009 – Cytomegalovirus infection

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 01/26/2018
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Cytomegalovirus infection - Oral Mucosal Lesion
See also in: Overview,Anogenital
Print 6 Images
View all Images (6)
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Cytomegalovirus infection (Systemic Symptoms) : Fever, Rash, ALT elevated, AST elevated, Atypical lymphocytosis, Lymphadenopathy, Malaise, Myalgia, Pharyngitis, LYP increased, MON increased
Clinical image of Cytomegalovirus infection
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