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Dermatosis papulosa nigra
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Dermatosis papulosa nigra

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Contributors: Naurin Ahmad MD, Lynn McKinley-Grant MD, Aída Lugo-Somolinos MD, Lowell A. Goldsmith MD, MPH
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Synopsis

Dermatosis papulosa nigra (DPN) are benign epidermal growths similar to seborrheic keratoses (SK). These lesions are typically asymptomatic and are most frequently seen on the cheeks. They are much more common in individuals of African and Asian descent. It is less frequently described in the white population, where SKs are more common. A 2007 study in Senegal of 30 patients with DPN found a genetic predisposition in 93%.

According to a 2003 study among Afro-Caribbean people, more participants with light phototypes (skin type V or less) had the lowest frequency of involvement. In addition to those with African heritage, the condition has also been reported in Filipino, Vietnamese, European, and Mexican individuals.

The onset of DPN is typically during adolescence, and women are affected more often than men. There may be a family history of similar lesions. The number of lesions typically increases with age; up to one-third of black adults have some of these lesions. Approximately 25% of patients with facial lesions will also have lesions at other body locations. 

DPN is a cosmetic concern only. In contrast to SKs, where rapid onset of numerous lesions can be a cutaneous sign of internal malignancy, multiple DPNs are not related to any systemic disease or syndrome.

For more information, see OMIM.

Codes

ICD10CM:
L82.1 – Other seborrheic keratosis

SNOMEDCT:
254669003 – Dermatosis papulosa nigra

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Last Updated: 10/25/2018
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Dermatosis papulosa nigra
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Dermatosis papulosa nigra : Cheek, Face, Neck, Smooth papules, Tiny papules, Hyperpigmented papules
Clinical image of Dermatosis papulosa nigra
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