Acute dystonic reactions are most commonly caused by neuroleptics, especially high-potency neuroleptics, but also antiemetics. The pathophysiology is most often linked with blockage of dopamine receptors. Other risk factors for acute dystonia include young age and male sex.
Management involves discontinuation of the triggering agent. Pharmacotherapy may include benztropine, diazepam, or diphenhydramine.
Related topics: Drug-induced movement disorders, Drug-induced muscle spasm.
G24.02 – Drug induced acute dystonia
G24.09 – Other drug induced dystonia
230315008 – Drug-induced dystonia