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Drug-induced abdominal pain
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Drug-induced abdominal pain

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Contributors: Michael W. Winter MD, Paritosh Prasad MD
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Synopsis

Abdominal pain may be associated with the use of a medication or other drug. Drug-induced abdominal pain is characterized by a sense of discomfort in the abdomen presenting soon after beginning a medication. Drugs that cause abdominal pain can also typically cause nausea, emesis, constipation, and diarrhea. In some cases, the pain may spontaneously self-resolve with continued use.

Persistent abdominal pain since starting a medication may be indicative of a more worrisome complication that warrants intervention, such as esophagitis, ulcer formation, colitis, perforation, cholecystitis, cholelithiasis, nephrolithiasis, pancreatitis, hepatitis, angioedema, chronic constipation, or anemia with chronic vascular compromise.

Many medications have been associated with abdominal pain (see Drug Reaction Data below), most commonly nonsteroidal anti-inflammatory drugs (NSAIDs).

Codes

ICD10CM:
R10.9 – Unspecified abdominal pain

SNOMEDCT:
21522001 – Abdominal pain

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 01/02/2018
Last Updated: 06/15/2018
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Drug-induced abdominal pain
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Drug-induced abdominal pain : Abdominal pain
Copyright © 2019 VisualDx®. All rights reserved.