The typical presentation of duodenal atresia in the neonate is with bilious vomiting and a scaphoid nondistended abdomen. Occasionally epigastric fullness is noted, and the vomiting may be nonbilious in up to 15% of cases.
Bile stain may be present in amniotic fluid from vomiting in utero. Polyhydramnios is associated with approximately 50% of cases. About one-third of neonates with duodenal atresia present with jaundice. Complications such as duodenal ileus may develop.
Duodenal atresia may occur with other congenital anomalies such as genitourinary or gastrointestinal disease, Down syndrome, congenital heart disease, and airway / respiratory disease. It is also linked to premature birth, low birth weight, growth arrest, and VACTERL association (vertebral, anorectal, cardiac, tracheo-esophageal, renal, and limb anomalies).
Management includes decompression, fluid draining, rehydration, and tube feeding. Repair may be made in laparoscopic or open surgery.
Q41.0 – Congenital absence, atresia and stenosis of duodenum
51118003 – Congenital atresia of duodenum