ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (26)
Early congenital syphilis - Skin
Print
Other Resources UpToDate PubMed

Early congenital syphilis - Skin

Print Images (26)
Contributors: Craig N. Burkhart MD, Dean Morrell MD, Lowell A. Goldsmith MD, MPH, Nancy Esterly MD
Other Resources UpToDate PubMed

Synopsis

Congenital syphilis, infection with the spirochete, Treponema pallidum, is acquired by the fetus, in utero, from an infected mother. Early congenital syphilis is defined as occurring before 2 years of age and is characterized by a variable number of cutaneous and extracutaneous findings. Half are asymptomatic at birth. Historically, infected infants were said to develop a form of rhinitis, snuffles, that is characterized by excessive blood stained nasal drainage by the infant's third week of life. Snuffles do not seem to occur with as much frequency as previously thought. Other findings include hepatomegaly, splenomegaly, lymphadenopathy, mucous patches, hemolytic anemia, thrombocytopenia, periostitis, and intrauterine growth retardation.

If syphilis remains latent and the infant does not exhibit symptoms until after 2 years of age, the course of the disease is different (late congenital syphilis). Findings include: tissue malformation at critical growth periods, incisor teeth abnormalities, corneal opacities, and eighth nerve deafness.

Codes

ICD10CM:
A50.9 – Congenital syphilis, unspecified

SNOMEDCT:
35742006 – Congenital syphilis

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Congenital rubella and newborn CMV infection. If blisters are present consider congenital candidiasis, acropustulosis of infancy, and congenital lyme disease.

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated: 04/18/2018
Copyright © 2019 VisualDx®. All rights reserved.
Early congenital syphilis - Skin
Print 26 Images Filter Images
View all Images (26)
(with subscription)
 Reset
Early congenital syphilis : Hepatosplenomegaly, Desquamation, Lymphadenopathy, Purple color, PLT decreased, RBC decreased
Clinical image of Early congenital syphilis
Copyright © 2019 VisualDx®. All rights reserved.