ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (29)
Eccrine poroma
Print Captions OFF
Other Resources UpToDate PubMed

Eccrine poroma

Print Images (29)
Contributors: Amanda Robinson MD, Alexa Kimball MD, Belinda Tan MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed


Eccrine poroma is a benign sweat gland tumor composed of uppermost glandular ductal cells of eccrine origin. The cells are keratinocytes from the lower portion of the acrosyringium of the eccrine duct. They fall into the category of poroid neoplasms, which includes the classic poroma, hidroacanthoma simplex, dermal duct tumor, and poroid hidroadenoma. They occur only in the skin and most often present as a skin colored or slightly erythematous smooth papule that may be sessile or pedunculated. Poromas are usually less than 2 cm in diameter and are slow growing or stable. Ulceration may occur, especially when they appear on points of pressure. Palms and soles are the most common sites for a poroma. Rarely, patients may develop multiple poromas, or eccrine poromatosis. This condition is characterized by more than 100 papules that may be distributed widely or confined to the palms and soles.

Poromas generally occur in adults over the age of 40 and can develop secondarily within a nevus sebaceus. There is no familial component and no apparent predilection for sex or race/ethnicity. No definitive pathogenesis has been described, but cases occurring after exposure to trauma or radiation or during pregnancy have been reported. Two variants, hidroacanthoma simplex and dermal duct tumor, have been described. Hidroacanthoma simplex is entirely confined within the epidermis, while dermal duct tumors are located entirely in the dermis. Rarely, malignant eccrine poroma, or porocarcinoma, develops – either spontaneously on normal skin or by transformation within a benign eccrine poroma. These lesions have metastatic potential.


D23.9 – Other benign neoplasm of skin, unspecified

399985004 – Eccrine poroma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

  • Squamous cell carcinoma
  • Basal cell carcinoma
  • Amelanotic melanoma
  • Seborrheic keratosis
  • Trichilemmoma
The histology of eccrine poromas is similar to that of hidradenoma, acrospiroma, and poroid hidradenoma.

Best Tests

Subscription Required

Management Pearls

Subscription Required


Subscription Required


Subscription Required

Last Updated: 04/09/2019
Copyright © 2019 VisualDx®. All rights reserved.
Eccrine poroma
Captions OFF Print 29 Images Filter Images
View all Images (29)
(with subscription)
Eccrine poroma : Palm, Smooth nodule, Smooth papule, Plantar foot
Clinical image of Eccrine poroma
A close-up of a smooth, deep pink papule.
Copyright © 2019 VisualDx®. All rights reserved.