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Eccrine spiradenoma - Skin
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Eccrine spiradenoma - Skin

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Contributors: Amanda Robinson MD, Alexa Kimball MD, Jeffrey D. Bernhard MD, Belinda Tan MD, PhD, Noah Craft MD, PhD, Lindy P. Fox MD, Lowell A. Goldsmith MD, MPH, Michael D. Tharp MD
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Synopsis

Eccrine spiradenoma is a rare, benign tumor of eccrine sweat glands. The characteristic clinical presentation is a painful, slow-growing, intradermal nodule on the head or trunk. The lesions typically appear between the second and fourth decades equally in males and females. They are usually small solitary lesions, but other patterns such as multiple lesions, zosteriform, Blaschkoid/linear, familial, congenital, or giant eccrine spiradenoma have uncommonly been reported. Spiradenomas have been reported in Brooke-Spiegler syndrome, an autosomal dominant condition characterized by development of multiple adnexal tumors, sometimes within the same lesion as a cylindroma. This association has led to the hypothesis that these tumors arise from a multipotent stem cell rather than from the eccrine gland. Malignant degeneration may occur but is very rare. Multiple spiradenomas are more likely to undergo malignant transformation than solitary lesions. Malignant spiradenomas tend to be larger and ulcerated and more commonly involve the trunk or extremities.

Codes

ICD10CM:
D23.9 – Other benign neoplasm of skin, unspecified

SNOMEDCT:
403938001 – Eccrine spiradenoma

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Last Updated: 07/01/2013
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Eccrine spiradenoma - Skin
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Eccrine spiradenoma : Head/neck, Smooth nodule, Tender skin lesion, Trunk, Painful skin lesion
Clinical image of Eccrine spiradenoma
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