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Empty sella syndrome
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Empty sella syndrome

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Contributors: Marilyn Augustine MD
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Synopsis

A syndrome characterized by flattening or regression of the pituitary gland within the sella turcica cavity, resulting in an MRI image of an empty sella turcica. This radiological finding may be associated with normal pituitary function.  Less commonly, pituitary surgery or abnormal formation of the pituitary gland may lead to pituitary hypofunction.

Codes

ICD10CM:
E23.6 – Other disorders of pituitary gland

SNOMEDCT:
237722004  – Empty Sella Syndrome

Differential Diagnosis & Pitfalls

This is a radiological finding rather than a medical condition. There is no evidence that patients with the radiological finding consistently have pituitary hormone abnormalities.
  • Sheehan syndrome
  • Consequence of radiation therapy or surgery to remove or shrink the pituitary
  • History of pituitary infraction
  • Congenital abnormality of a transcription factor necessary for pituitary differentiation, such as PROP-1

Best Tests

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References

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Last Updated: 08/05/2016
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Empty sella syndrome
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Empty sella syndrome : Headache
Imaging Studies image of Empty sella syndrome
MRI demonstrating empty sella turcica.
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