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Erythema gyratum repens - Skin
See also in: Immunocompromised, HIV and AIDS
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Erythema gyratum repens - Skin

See also in: Immunocompromised, HIV and AIDS
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Contributors: Noah Craft MD, PhD, Lindy P. Fox MD, Lowell A. Goldsmith MD, MPH, Michael D. Tharp MD
Other Resources UpToDate PubMed

Synopsis

Erythema gyratum repens (Gammel disease) is a paraneoplastic syndrome that is thought to arise as a result of the cross-reactivity of tumor antigens with antigens in the skin. It often presents prior to the detection of the internal malignancy as a pruritic, annular, erythematous eruption whose edges advance at a rapid rate.

Erythema gyratum repens is associated with internal malignancy in 85% of patients, most commonly lung carcinoma. Other cases have been reported with cancers of the esophagus, breast, cervix, stomach, pharynx, bladder, prostate, uterus, tongue, colon, and pancreas. Erythema gyratum repens has also been noted in association with several nonmalignant conditions such as tuberculosis, linear IgA dermatosis, psoriasis, pityriasis rubra pilaris, pemphigus vulgaris, bullous pemphigoid, ichthyosis, and hypereosinophilic syndrome. The disorder has only been reported in whites. The male-to-female ratio is 2:1, and the average age of onset is 63 years.

Codes

ICD10CM:
L53.8 – Other specified erythematous conditions

SNOMEDCT:
77300003 – Erythema gyratum repens

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

The differential includes other figurate erythemas:

Best Tests

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Management Pearls

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Therapy

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References

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Last Updated: 01/23/2015
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Erythema gyratum repens - Skin
See also in: Immunocompromised, HIV and AIDS
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View all Images (13)
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Erythema gyratum repens : Erythema, Fine scaly plaque, Serpiginous configuration, Symmetric extremities, Trunk, Pruritus
Clinical image of Erythema gyratum repens
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