Erythema gyratum repens (EGR), also known as Gammel disease, is a rare figurate erythema that is considered a paraneoplastic condition in 70% of cases. EGR most often occurs several months prior to the diagnosis of an underlying malignancy; however, it may also occur along with an already established cancer. The pathogenesis of EGR is not well-established, but it is thought to be due to an immune response in the skin that is triggered by an underlying malignancy. EGR presents as a pruritic, annular, erythematous eruption with edges that advance at a rapid rate.

EGR is associated with internal malignancy in 70% of patients. EGR is most commonly associated with lung cancer, followed by esophageal cancer and breast cancer. EGR has also been noted in association with several nonmalignant conditions such as tuberculosis, autoimmune bullous diseases, CREST syndrome, psoriasis, pityriasis rubra pilaris, ichthyosis, and hypereosinophilic syndrome. The male-to-female ratio is 2:1, and the average age of onset is in the seventh decade.