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Essential thrombocytosis
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Essential thrombocytosis

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Contributors: Carla Casulo MD
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Synopsis

Essential thrombocytosis is a chronic myeloproliferative disorder characterized by abnormal proliferation of platelets that originate from clonal proliferation of megakaryocytes in the bone marrow. Patients have significantly elevated platelet counts and may also have increased white blood cell counts. The condition may present with anemia, splenomegaly, and abdominal pain. Patients may have bleeding or bruising and sometimes, depending on the platelet count, may also have thrombosis. The JAK2 mutation may be present.

Depending on risk, treatment may involve aspirin, hydroxyurea, or anagrelide.

Codes

ICD10CM:
D47.3 – Essential (hemorrhagic) thrombocythemia

SNOMEDCT:
109994006 – Essential Thrombocytosis

Differential Diagnosis & Pitfalls

Best Tests

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Therapy

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References

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Last Reviewed: 03/09/2017
Last Updated: 03/09/2017
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Essential thrombocytosis
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Essential thrombocytosis : Headache, Syncope, Amaurosis fugax, Paresthesias, Presyncope, Atypical chest pain, PLT increased
Copyright © 2018 VisualDx®. All rights reserved.