Fordyce spots are normal, superficial, ectopic sebaceous glands seen on mucosal surfaces that are not associated with hair follicles. They may affect as much as 80% of the population. Fordyce spots are often found on the oral mucosa, the vermilion of the lips, the inferior eyelids, and the genitals. The spots are usually clustered and asymptomatic.

The likelihood of developing Fordyce spots increases with age; however, these small papules can be seen in patients of any age. Their development can be associated with hormonal changes, and puberty can bring about their onset.