ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences
Germinoma
Print
Other Resources UpToDate PubMed

Germinoma

Print Images (1)
Contributors: Andrea Wasilewski MD, Jamie Adams MD, Richard L. Barbano MD, PhD
Other Resources UpToDate PubMed

Synopsis

Germinoma is a malignant germ cell tumor arising in the midline, largely in the pineal or suprasellar regions of the central nervous system, characterized by the presence of primitive, large, malignant germ cells and lymphocytes. Germinomas can often cause obstructive hydrocephalus presenting with severe headache, nausea, vomiting, papilledema, and changes in mental status. Other findings include ataxia, fatigue, upward gaze paralysis, increased intracranial pressure, and vision loss. Germinomas occur in young patients between the ages of 10 and 20, with males affected more often than females.

Treatment includes surgical resection, radiation, and chemotherapy. Germinomas may reoccur after therapy.

Codes

ICD10CM:
C71.6 – Malignant neoplasm of cerebellum

SNOMEDCT:
28307001 – Germinoma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed: 03/11/2019
Last Updated: 05/10/2019
Copyright © 2019 VisualDx®. All rights reserved.
Germinoma
Print 1 Images
Germinoma : Headache, Papilledema, Personality changes, Anorexia, Upward gaze paralysis
Copyright © 2019 VisualDx®. All rights reserved.