ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (20)
Hereditary acrodermatitis enteropathica - Anogenital in
See also in: Skin
Print
Other Resources UpToDate PubMed

Hereditary acrodermatitis enteropathica - Anogenital in

See also in: Skin
Print Images (20)
Contributors: Mary Spencer MD, Ann Lenane MD, Sireesha Reddy MD, Amy Swerdlin MD, Manasi Kadam Ladrigan MD, Carol Berkowitz MD
Other Resources UpToDate PubMed

Synopsis

Hereditary acrodermatitis enteropathica is an eczematous dermatitis on the face, hands, feet, and anogenital area, caused by zinc deficiency. It is attributed to an autosomal recessive inherited disorder of zinc absorption, due to abnormal zinc binding ligands. It usually occurs days to weeks after birth in infants given cow's milk. In breast-fed infants, it can occur soon after the transition to cow's milk.

Identical clinical findings may result from acquired zinc deficiency due to other causes. It may be seen in premature infants who are exclusively breast fed in the setting of increased metabolic demands and declining levels of zinc in the mother's breast milk. Zinc deficiency has rarely been linked to a defect in the transfer of zinc into breast milk. Historically, it was seen in infants receiving parenteral nutrition, although zinc supplementation has now become routine. Clinicians should be aware of the possibility that hereditary acrodermatitis enteropathica can be mimicked in infants receiving parenteral nutrition formulations because of a disease such as biliary atresia.

Codes

ICD10CM:
E83.2 – Disorders of zinc metabolism

SNOMEDCT:
37702000 – Hereditary acrodermatitis enteropathica

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated: 04/19/2018
Copyright © 2019 VisualDx®. All rights reserved.
Hereditary acrodermatitis enteropathica - Anogenital in
See also in: Skin
Print 20 Images Filter Images
View all Images (20)
(with subscription)
 Reset
Hereditary acrodermatitis enteropathica : Diarrhea, Rash, Acral, Failure to thrive, Irritability, Skin erosion
Clinical image of Hereditary acrodermatitis enteropathica
Copyright © 2019 VisualDx®. All rights reserved.