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Herpes simplex virus blepharitis - External and Internal Eye
See also in: Cellulitis DDx
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Herpes simplex virus blepharitis - External and Internal Eye

See also in: Cellulitis DDx
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Contributors: Brandon D. Ayres MD, Christopher Rapuano MD, Harvey A. Brown MD, Sunir J. Garg MD, Lauren Patty Daskivich MD, MSHS
Other Resources UpToDate PubMed

Synopsis

Herpes simplex virus blepharitis is an infection of the eyelid(s) with either HSV-1 or HSV-2 (less common). There is erythema and vesiculation of the eyelids and periocular skin. Presenting symptoms include pain and tenderness upon palpation of the affected area. There is increased lacrimation in severe cases.

The spectrum of ocular herpetic disease also includes conjunctivitis, iritis, and keratitis. Epithelial keratitis involves only the superficial layer of the cornea and although less severe still can lead to scarring and vision loss. Stromal keratitis, however, involves deeper layers of the cornea and also may lead to vision loss.

Primary ocular HSV infections occur most often in children between the ages of 6 months and 5 years, and such infections almost always present as blepharitis or blepharoconjunctivitis. Keratitis is more commonly seen in recurrent attacks. There have been several reports of recurrent HSV blepharitis, however.

The treatment of HSV blepharitis is supportive as most cases, are self-limiting, and resolve within 2–3 weeks. Corneal involvement with HSV necessitates treatment with antiviral agents to prevent complications.

Differentiate this condition from preseptal or orbital cellulitis on the basis of vesicles and ulcerations.

Codes

ICD10CM:
B00.59 – Other herpesviral disease of eye

SNOMEDCT:
186544000 – Herpesviral blepharitis

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Last Updated: 06/15/2018
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Herpes simplex virus blepharitis - External and Internal Eye
See also in: Cellulitis DDx
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Herpes simplex virus blepharitis (HSV Blepharitis) : Eye pain, Eyelid edema, Unilateral, Conjunctival injection, Vesicles
Clinical image of Herpes simplex virus blepharitis
Grouped pustules on an erythematous base on the upper eyelid.
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