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Inclusion body myositis
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Inclusion body myositis

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Contributors: Pamela L. Sloan MD
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Synopsis

Slowly progressive inflammatory degenerative muscle disorder involving weakness of skeletal muscles and the abnormal presence of vacuoles, amyloid (and other protein) deposits, and filamentous inclusion bodies in muscle fiber. It is the most common acquired inflammatory muscle disorder in the over-50 age group. Distal muscle atrophy and weakness are typically seen first in quadriceps with difficulty walking, climbing, and rising from a seated position, and eventually with falls. Finger flexor weakness interferes with gripping. More distal and proximal muscle groups are impacted as the disease progresses. Dysphagia may become severe enough to interfere with nutrition.

While most cases occur sporadically, rare familial occurrences have been reported. Management consists largely in easing symptoms, exercise therapy, use of mobility devices, and medications.

Codes

ICD10CM:
G72.41 – Inclusion body myositis [IBM]

SNOMEDCT:
72315009 – Inclusion Body Myositis

Diagnostic Pearls

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Best Tests

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References

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Last Updated: 02/04/2016
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Inclusion body myositis
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Inclusion body myositis : Developed chronically lasting months to years, Distal muscle weakness, Muscle atrophy, No acute distress, Proximal muscle weakness, Dysphagia, Myalgia
Copyright © 2019 VisualDx®. All rights reserved.