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Irritant contact dermatitis - Anogenital in
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Irritant contact dermatitis - Anogenital in

See also in: Overview,External and Internal Eye
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Contributors: Jeffrey M. Cohen MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Irritant contact dermatitis is a reaction caused by direct physical or chemical injury to the epidermis. The damage caused by an irritant leads to inflammation, manifested in the skin as erythema, edema, and scaling. Irritant contact dermatitis should be differentiated from true allergic contact dermatitis, which is a delayed type-IV hypersensitivity (immune) reaction.

Contact dermatitis of the penis is more often of the irritant type rather than allergic due to the persistent moisture and maceration in the genital region. Most males are susceptible to irritant dermatitis.

Soaps, detergents, antiseptic solutions, and topical medications are often the source of irritation. Prolonged or recurrent exposure to an irritant often causes the skin to become lichenified, hyperkeratotic, and inflamed.

Early in the course of irritant contact dermatitis, patients typically present complaining of a burning or stinging; the symptoms and skin eruption usually follow the exposure by hours if the irritant is strong (whereas in allergic contact dermatitis, symptoms are usually delayed by approximately 2 days following exposure). As the irritation becomes chronic and the skin continually inflamed, pruritus can become a predominant symptom.

Codes

ICD10CM:
L24.9 – Irritant contact dermatitis, unspecified cause

SNOMEDCT:
110979008 – Primary irritant dermatitis

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 08/14/2017
Last Updated: 08/16/2017
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Irritant contact dermatitis - Anogenital in
See also in: Overview,External and Internal Eye
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View all Images (5)
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Irritant contact dermatitis : Burning skin sensation, Erythema, Intertriginous, Pruritus, Scaly plaques
Clinical image of Irritant contact dermatitis
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