Jessner benign lymphocytic infiltrate - Skin
The etiology and pathophysiology of JLIS are not well understood.
There is no known predilection for males versus females or a particular ethnicity or socioeconomic status. JLIS typically occurs in adults in their 30s and 40s and is quite rare in children. It may be photoexacerbated in some individuals.
Individual lesions tend to resolve over weeks to months, and the cutaneous manifestations of JLIS tend to resolve over years.
L98.6 – Other infiltrative disorders of the skin and subcutaneous tissue
19719003 – Benign lymphocytic infiltration of Jessner
- Subacute cutaneous lupus erythematosus - Usually has scaly plaques.
- Tumid lupus – Abundant dermal mucin on histopathology, but may be hard to distinguish from JLIS.
- Polymorphous light eruption – Favors extensor arms and displays dermal edema on histopathology.
- Cutaneous lymphoid hyperplasia – Dense nodular lymphocytic infiltrate on histopathology.
- Erythema migrans (Lyme disease) – Usually a solitary lesion associated with tick bite.
- Granuloma faciale – Neutrophils and eosinophils on histopathology.
- Leukemia cutis – Monoclonal population of lymphocytes.
- Cutaneous lymphoma – Monoclonal population of lymphocytes.
- Reticular erythematous mucinosis – Clinically, it has a reticular appearance.