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Lobomycosis
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Lobomycosis

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Contributors: Edith Lederman MD, Noah Craft MD, PhD
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Synopsis

Lobomycosis, also known as Jorge Lobo's disease or keloidal blastomycosis, is a chronic cutaneous and subcutaneous fungal disease endemic to tropical and subtropical regions of Central and South America. The organism, Lacazia loboi (previously Loboa loboi), is a fungus, which, to date, can be cultured only in vivo.

The onset of lobomycosis is insidious and progresses over decades. The incubation period is months to years. The fungus grows at temperatures less than 37°C, such that spread of the infection systemically does not occur. There is often a history of antecedent trauma and subsequent environmental exposure (often water).

There is a strong male predominance (approximately 90% of cases), probably related to occupational exposure (ie, agriculture).

There may be genetic factors increasing the risk of infection as certain Native American tribes of Brazil are frequently infected; however, specific genetic markers have not been identified. This disease is very rare in travelers, and the first case in an American traveler was reported in 2000.

Codes

ICD10CM:
B48.0 – Lobomycosis

SNOMEDCT:
47306003 – Lobomycosis

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Last Updated: 07/11/2017
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Lobomycosis
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Lobomycosis : Ankle, Developed chronically lasting months to years, Smooth nodule, Raised scar, Ears
Clinical image of Lobomycosis
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