Lupus panniculitis - Skin in Adult
Lupus panniculitis develops in 2% to 5% of patients with systemic lupus erythematosus (SLE). Cutaneous manifestations of lupus panniculitis can develop years before or years after a diagnosis of SLE. Lupus panniculitis is not limited to patients with SLE.
In adults, the face, proximal extremities, trunk, and buttocks are most commonly affected. Average age of onset is late 30s to early 40s. The condition is more common in women (similar to other forms of lupus erythematosus).
L93.2 – Other local lupus erythematosus
239888002 – Lupus panniculitis
- Morphea – usually presents with purplish borders, fewer nodules, and less facial involvement
- Sarcoidosis – less induration, more epithelial changes
- Subcutaneous panniculitis-like T-cell lymphoma
- Other types of panniculitis – requires pathologic tissue examination to differentiate
- Jessner's lymphocytic infiltration of the skin – smoother, well-demarcated, infiltrated red plaques
- Tumid lupus erythematosus – photosensitive distribution of erythematous papules, nodules, and plaques
- Annular erythema – expanding annular lesions with raised red (and sometimes scaling) borders and central clearing, associated with lupus erythematosus
- Lipoatrophy – associated with history of injected medications or of highly active anti-retroviral therapy treatment for HIV