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Lymphomatous meningitis
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Lymphomatous meningitis

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Contributors: Benjamin L. Mazer MD, MBA, Jamie Adams MD, Richard L. Barbano MD, PhD
Other Resources UpToDate PubMed

Synopsis

The spread of lymphoma to the leptomeninges, either around the brain, spinal cord, or nerve roots. This can occur as either a focal area or diffusely along the meninges. Symptoms include headache, mental status changes, seizure, cranial nerve dysfunction, or symptoms of spinal cord dysfunction. One feared complication of lymphomatous meningitis is communicating hydrocephalus and subsequent increased intracranial pressure.

In contrast to infectious meningitis, fever is often absent. Leptomeningeal involvement can occur in both lymphomas primary to the central nervous system (CNS) and in those secondarily invading the CNS. Lymphomas rarely begin in the leptomeninges. Presence of leptomeningeal involvement of the lymphoma may affect prognosis and treatment decisions.

Codes

ICD10CM:
C79.32 – Secondary malignant neoplasm of cerebral meninges

SNOMEDCT:
426128009  – Lymphomatous meningitis

Differential Diagnosis & Pitfalls

Best Tests

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References

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Last Updated: 11/14/2018
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Lymphomatous meningitis
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Lymphomatous meningitis : Headache, Cranial nerve palsy, Memory loss
Copyright © 2018 VisualDx®. All rights reserved.