ContentsSynopsisCodesBest TestsReferences
May-Hegglin anomaly
Print
Other Resources UpToDate PubMed

May-Hegglin anomaly

Print Images (1)
Other Resources UpToDate PubMed

Synopsis

A rare autosomal dominant genetic disorder characterized by giant platelets, thrombocytopenia, and leukocytes with Dohle body inclusions. Caused by abnormalities in gene MYH9. Signs and symptoms include prolonged bleeding time, purpura, epistaxis, gingival hemorrhage, intracranial bleeding, menorrhagia, and easy bruising. Patients can be asymptomatic, or symptoms may present at birth. Males and females are equally affected. Treatment is only required during episodes of substantial bleeding. Precautions in case of excess bleeding should be taken with pregnant women and during surgery or dental work. Closely related to Sebastian syndrome, Fechtner syndrome, and Epstein syndrome.

For more information, see OMIM.

Codes

ICD10CM:
D72.0 – Genetic anomalies of leukocytes

SNOMEDCT:
234484005 – May–Hegglin Anomaly

Best Tests

Subscription Required

References

Subscription Required

Last Updated: 03/29/2017
Copyright © 2019 VisualDx®. All rights reserved.
May-Hegglin anomaly
Print 1 Images
May-Hegglin anomaly : Bleeding time prolonged, Easy bruising, Ecchymosis, Menorrhagia, Gingival bleeding, PLT decreased, Recurrent epistaxis
Copyright © 2019 VisualDx®. All rights reserved.