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Melasma
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Melasma

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Contributors: Lauren Ko, Stephanie Diamantis MD, Susan Burgin MD
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Synopsis

Melasma is an acquired disorder of hyperpigmentation typically affecting sun-exposed areas of the face. The condition is more common in women with darker skin phototypes (including those of Hispanic and Asian descent). Melasma rarely occurs before puberty, with onset most often in the reproductive years. It has also been rarely reported in males.

Melasma is characterized by irregularly bordered, evenly pigmented tan macules on the face. Darker macules may sometimes be seen ("dermal melasma"). Although the pathophysiology of melasma is poorly understood, thyroid autoimmunity, ultraviolet radiation, hyperestrogenism (pregnancy, contraception), genetics, and anti-epileptic medications are known to be contributing factors.

Codes

ICD10CM:
L81.1 – Chloasma

SNOMEDCT:
36209000 – Melasma

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 07/11/2017
Last Updated: 07/11/2017
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Melasma
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Melasma : Superior lip, Hyperpigmented patches, Cheeks
Clinical image of Melasma
An evenly pigmented tan patch on the upper cutaneous lip.
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