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Metastatic cutaneous carcinoma
See also in: External and Internal Eye,Hair and Scalp
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Metastatic cutaneous carcinoma

See also in: External and Internal Eye,Hair and Scalp
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Contributors: Noah Craft MD, PhD, Lindy P. Fox MD, Belinda Tan MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Approximately 1%-4.5% of internal cancers metastasize to the skin. The most frequent primary tumors are carcinomas of the breasts, stomach, lungs, uterus, kidneys, ovaries, colon, or bladder. The lesions may represent direct extension to the skin, or local or distant metastasis via lymphatic or hematogenous dissemination of tumor cells.

Cutaneous metastases usually indicate a very poor prognosis, with patients often succumbing to their disease within 3-6 months. Patients may be any age but are typically older. The interval between detection of the primary tumor and development of cutaneous metastases may be on the order of years, or skin metastases may be the first manifestation of an internal malignancy.

In addition to the skin lesion(s), patients with previously undiagnosed cancer may also notice a palpable mass, pallor, or weight loss. A personal history of previous carcinoma provides an important diagnostic clue.

Codes

ICD10CM:
C79.2 – Secondary malignant neoplasm of skin

SNOMEDCT:
79282002 – Secondary carcinoma

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Differential Diagnosis & Pitfalls

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Therapy

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References

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Last Updated: 10/24/2018
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Metastatic cutaneous carcinoma
See also in: External and Internal Eye,Hair and Scalp
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Metastatic cutaneous carcinoma (Orbital) : Eye pain, Blurred vision, Diplopia, Eyelid edema, Eyelid ptosis, Limited ocular motility, Periorbital edema, Unilateral, Vision loss, Proptosis
Clinical image of Metastatic cutaneous carcinoma
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