ContentsSynopsisCodesBest TestsDrug Reaction DataReferences
Minimal change disease
Print
Other Resources UpToDate PubMed

Minimal change disease

Print Images (1)
Contributors: Catherine Moore MD
Other Resources UpToDate PubMed

Synopsis

The most common cause of nephrotic syndrome in children, this glomerular disease is characterized by normal glomerular appearance by light microscopy, no immune complexes on immunofluorescence, and diffuse podocyte foot process effacement on electron microscopy. Minimal change disease can also present in adulthood and is classically very responsive to steroids. The pathophysiology is not clear, but T-cell dysfunction is thought to be a significant factor.

Codes

ICD10CM:
N05.0 – Unspecified nephritic syndrome with minor glomerular abnormality

SNOMEDCT:
44785005 – Minimal change disease

Best Tests

Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required

References

Subscription Required

Last Updated: 02/12/2016
Copyright © 2019 VisualDx®. All rights reserved.
Minimal change disease
Print 1 Images
Minimal change disease : Facial edema, Microscopic hematuria, Proteinuria, Weight gain, BP increased
Copyright © 2019 VisualDx®. All rights reserved.