Molluscum contagiosum - Anogenital in
Molluscum contagiosum is a viral skin infection caused by a DNA poxvirus. It manifests as smooth firm papules with a central umbilication. Genital lesions are most commonly spread by sexual contact, and papules are most commonly seen on the shaft of the penis. However, lesions may also be found on the scrotum, in the pubic area, and on the inner aspect of the thighs.
Molluscum contagiosum may also be spread by direct contact (most often in children) and autoinoculation. Infections have also been associated with swimming pool facilities via fomites.
Many cases are asymptomatic, but there can be surrounding irritation in association with pruritus. Molluscum may occur in tattoos. Papules may persist for several months and up to 2 years before disappearing. In the immunocompetent host, the disease tends to be self-limited.
B08.1 – Molluscum contagiosum
40070004 – Molluscum contagiosum
- Condyloma acuminatum can look similar if small and acrochordons may appear similar as well.
- Herpes simplex lesions can resemble molluscum with a central umbilication, but lesions are fluid-filled rather than solid as in molluscum contagiosum.
- Fordyce spots
- Milia tend to be whiter in color and more concentrated on the face.
- Lobular capillary hemangioma (pyogenic granuloma) is obviously vascular with frequent ulceration.
- Lichen planus lesions are purple, pruritic planar papules that can also spread in a linear pattern.
- Basal cell carcinoma tends to be solitary.
- Keratoacanthomas have a central keratin core and grow rapidly.
- Pearly penile papule lesions, in most cases, are on the coronal sulcus but can be found elsewhere on the penis. Consider a diagnosis of pearly penile papules even if the lesions reside outside of the coronal sulcus, especially if the lesions are unresponsive to treatment for molluscum contagiosum.
- Cryptococcal infection in an immunocompromised host.
- Lichen nitidus
- Bowenoid papule
- Papular acantholytic dermatosis