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Nasal polyp in Adult
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Nasal polyp in Adult

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Contributors: Eulalia Amador MD, Paul C. Bryson MD
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Synopsis

Nasal polyps are benign, often bilateral sessile or pedunculated semitranslucent mucosal outgrowths of the nasal cavity and paranasal sinuses. They occur in 1%-4% of the general population, with peak incidence in individuals between the ages of 20 and 40 years.

The majority of cases are associated with edema and eosinophilic infiltration. Although the precise cause of formation is unknown, the etiology of nasal polyps is regarded as multifactorial and as being linked with chronic mucosal inflammation. Contributing factors may include cytokine mediators, innate immune defects, infection, genetic factors, environmental exposures, and inflammatory conditions.

Nasal polyps are frequently associated with chronic sinusitis, asthma, aspirin sensitivity, nonallergic (eg, vasomotor, drug induced) and allergic rhinitis and rhinosinusitis, cystic fibrosis, and alcohol intolerance.

Codes

ICD10CM:
J33.9 – Nasal polyp, unspecified

SNOMEDCT:
736499003 – Polyp of nasal cavity and/or nasal sinus

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Other tumors:

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 03/05/2018
Last Updated: 05/23/2019
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Nasal polyp in Adult
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Nasal polyp : Nasal congestion, Nasal obstruction, Nasal polyps, Recurring episodes or relapses, Hyposmia
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