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Neonatal lupus erythematosus - Skin
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Neonatal lupus erythematosus - Skin

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Contributors: Belinda Tan MD, PhD, Craig N. Burkhart MD, Dean Morrell MD, Lowell A. Goldsmith MD, MPH, Nancy Esterly MD
Other Resources UpToDate PubMed

Synopsis

This summary discusses neonatal lupus erythematosus. Systemic lupus erythematosus in adults and children is addressed separately.

Neonatal lupus erythematosus is an autoimmune disorder of the newborn caused by maternal autoantibodies. Anti-SSA/Ro, anti-SSB/La, and anti-U1RNP antibodies can be found in both the fetal and maternal circulation. The main concern in patients with neonatal lupus is congenital heart block, which is irreversible in almost all cases. Elevated liver enzymes, thrombocytopenia, anemia, and neutropenia may also be seen. These will resolve as the maternal antibodies are cleared, usually between the ages of 6–8 months.

Codes

ICD10CM:
L93.2 – Other local lupus erythematosus

SNOMEDCT:
95609003 – Neonatal lupus erythematosus

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Last Updated: 06/13/2016
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Neonatal lupus erythematosus - Skin
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Neonatal lupus erythematosus : Erythema, Fine scaly plaque, Forehead
Clinical image of Neonatal lupus erythematosus
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