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Oculoglandular syndrome of Parinaud
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Oculoglandular syndrome of Parinaud

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Contributors: Kristina Voss MD, Deepak Sobti MD
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Synopsis

Oculoglandular syndrome of Parinaud (OSP) is a unilateral conjunctivitis that presents with ipsilateral preauricular and submandibular lymphadenopathy. Conjunctival granulomas and fever also typically occur with this syndrome. It is primarily bacterial in etiology. It is estimated to affect 22 000 people annually in the United States. The most common bacterial cause is Bartonella henselae, which is called cat-scratch disease due to contraction from exposure to cats and their fleas. Transmission does not require a scratch but can occur with a cat lick or bite or simply contact with a cat's fleas. Human transmission does not occur. Other implicated bacteria include Mycobacterium tuberculosis, Francisella tularensis, and Treponema pallidum. Coccidioides can be a nonbacterial cause of the disease.

Symptoms typically begin with conjunctivitis approximately 3-10 days after inoculation. Lymphadenopathy may occur simultaneously or 1-2 weeks after conjunctivitis. The lymphadenopathy may become suppurative in approximately 10%-40% of cases. It rarely can progress to severe disseminated infection requiring hospitalization.

Codes

ICD10CM:
H10.89 – Other conjunctivitis

SNOMEDCT:
128350005 – Bacterial conjunctivitis

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Last Reviewed: 08/30/2017
Last Updated: 08/30/2017
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Oculoglandular syndrome of Parinaud
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Oculoglandular syndrome of Parinaud : Fever, Regional lymphadenopathy, Unilateral
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