ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (9)
Oral lupus erythematosus - Oral Mucosal Lesion
Print
Other Resources UpToDate PubMed

Oral lupus erythematosus - Oral Mucosal Lesion

Print Images (9)
Contributors: Belinda Tan MD, PhD, Carl Allen DDS, MSD, Sook-Bin Woo MS, DMD, MMSc
Other Resources UpToDate PubMed

Synopsis

Lupus erythematosus is a chronic inflammatory autoimmune disease that can manifest cutaneously, orally, and systemically. Risk factors for developing cutaneous lesions include sex (3:1 female-to-male ratio, especially during child-bearing years) and race/ethnicity, with black patients demonstrating a higher incidence compared with white patients. Cutaneous lupus erythematosus may be acute, subacute, or chronic (also known as discoid). Sex and race/ethnicity are also risk factors for developing systemic lupus erythematosus (SLE), with a 6:1 female-to-male ratio, and with black women demonstrating a fourfold higher incidence compared with white women. Women of child-bearing potential are most commonly affected. Lupus erythematosus can also be drug induced.

Oral mucosal lesions can occur in both cutaneous and systemic forms of lupus erythematosus. The lips, gingiva, tongue, and palatal and buccal mucosa are the most commonly involved sites.

For a more in-depth discussion of the subtypes of cutaneous lupus erythematosus and of SLE, see Discoid Lupus Erythematosus, Subacute Cutaneous Lupus Erythematosus, and Systemic Lupus Erythematosus in VisualDx. See also Drug Induced Lupus Erythematosus in VisualDx.

Codes

ICD10CM:
L93.2 – Other local lupus erythematosus

SNOMEDCT:
403495008 – Discoid lupus erythematosus of oral mucosa

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

The oral lesions of lupus erythematosus could be confused with other superficial oral ulcerative conditions such as lichen planus, hypersensitivity reactions, or even aphthous ulcers. However, the oral lesions of lupus erythematosus almost never occur without concomitant skin lesions or systemic involvement. 

Because patients with SLE may have been treated with immunosuppressive therapy for years, patients should be evaluated for erythroplakia, erythro-leukoplakia, and squamous cell carcinoma.

Differential diagnosis of oral lesions:
If patients have dry eyes or dry mouth, they should be evaluated for concomitant Sjögren syndrome.

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated: 01/31/2013
Copyright © 2019 VisualDx®. All rights reserved.
Oral lupus erythematosus - Oral Mucosal Lesion
Print 9 Images
View all Images (9)
(with subscription)
Oral lupus erythematosus : Oral ulcers, Mouth pain, Oral burning sensation
Clinical image of Oral lupus erythematosus
Copyright © 2019 VisualDx®. All rights reserved.