Oral lupus erythematosus - Oral Mucosal Lesion
Oral mucosal lesions can occur in both cutaneous and systemic forms of lupus erythematosus. The lips, gingiva, tongue, and palatal and buccal mucosa are the most commonly involved sites.
For a more in-depth discussion of the subtypes of cutaneous lupus erythematosus and of SLE, see Discoid lupus erythematosus, Subacute cutaneous lupus erythematosus, and Systemic lupus erythematosus. See also Drug-induced lupus erythematosus.
L93.2 – Other local lupus erythematosus
403495008 – Discoid lupus erythematosus of oral mucosa
Differential Diagnosis & Pitfalls
Because patients with SLE may have been treated with immunosuppressive therapy for years, patients should be evaluated for erythroplakia, erythro-leukoplakia, and squamous cell carcinoma.
Differential diagnosis of oral lesions:
- Erosive lichen planus
- Mucous membrane pemphigoid
- Pemphigus vulgaris
- Erythroplakia – usually unilateral
- Squamous cell carcinoma – usually unilateral