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Osteonecrosis of the femoral heads in Adult
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Osteonecrosis of the femoral heads in Adult

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Synopsis

Osteonecrosis, or avascular necrosis, of the femoral head is an infarction of the bone due to disruption of blood flow. Patients present with a progressive limp or reduced range of motion at the hip. The amount of pain can vary substantially and is often referred to the knee.

Osteonecrosis of the femoral head can be unilateral or bilateral and can occur in adults or children. When it occurs in children, it is called Legg-Calve-Perthes disease. Osteonecrosis of the femoral head may be secondary to trauma (fracture, dislocation), but also frequently occurs without trauma, making diagnosis more difficult. Common nontraumatic causes include alcohol abuse, corticosteroids, sickle cell disease, and autoimmune disease.

Osteonecrosis of the femoral head can lead to complete destruction of the bone and requires immediate specialist evaluation. Surgical interventions, such as osteotomy, decompression, or reconstruction, are typically required.

For more information, see OMIM.

Codes

ICD10CM:
M87.859 – Other osteonecrosis, unspecified femur

SNOMEDCT:
240196003 – Bone necrosis

Differential Diagnosis & Pitfalls

Best Tests

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 03/29/2017
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Osteonecrosis of the femoral heads in Adult
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Osteonecrosis of the femoral heads : Flank pain, Bone pain, Groin pain, Inability to bear weight, Arthralgia, Buttock pain, Limited range of motion
Imaging Studies image of Osteonecrosis of the femoral heads
Serpiginous geographic sclerosis with lucent center involving the subchondral portion of the left femoral head compatible with AVN.
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